How to Use Litfulo for Alopecia Areata Treatment in the US 2025

Alopecia areata affects over 6.8 million people in the United States, causing sudden hair loss in patches on the scalp, face, or body, according to the National Alopecia Areata Foundation 2025 data. Many in states like California or New York seek effective treatments to manage symptoms and promote regrowth. Litfulo (ritlecitinib), an oral JAK inhibitor approved by the FDA in 2023 for severe alopecia areata in patients 12 and older, offers a targeted approach. This medication reduces inflammation around hair follicles, allowing regrowth in many cases. This guide explains how to use Litfulo for alopecia areata treatment, based on clinical trial results and dermatologist recommendations.

What Litfulo Does for Alopecia Areata

Litfulo alopecia treatment medicine works by blocking enzymes (JAK3 and TEC family) that drive immune attacks on hair follicles. In alopecia treatment Litfulo targets the root cause of patchy loss. Ritlecitinib alopecia treatment 2025 continues to show promise for severe cases, including alopecia totalis (full scalp loss) or universalis (total body loss).

Dosing and Administration

Litfulo comes as a once-daily oral capsule. The standard dose for adults and adolescents 12+ is 50 mg, taken with or without food. Consistency matters—take at the same time daily for steady levels. Capsules should be swallowed whole, not crushed. Doctors may start with a loading dose or adjust based on response. Storage at room temperature away from moisture keeps it effective.

Litfulo Clinical Trial Results

Phase 3 trials for Litfulo hair regrowth demonstrated significant improvement. Over 23% of patients achieved 80% scalp coverage after 6 months, compared to 1.6% on placebo. Many saw initial regrowth in 3 months. Results held for eyebrows and eyelashes in some. Long-term data from 2025 extensions show sustained benefits for responders.

Monitoring Progress

Dermatologists track with photos and SALT scores (Severity of Alopecia Tool). Visits every 3-6 months assess growth and side effects. Patience helps—full effects take 6-12 months.

Common Side Effects and Management

Side effects include:

  • Upper respiratory infections  
  • Headache or acne  
  • Elevated liver enzymes (monitored via blood tests)

Most are mild; infections may need antibiotics. Avoid live vaccines during treatment.

Lifestyle Support During Treatment

Balanced diet with biotin-rich foods (eggs, nuts) aids hair health. Stress reduction through yoga or meditation complements therapy. Gentle hair care avoids further loss.

Who May Benefit

Litfulo suits severe alopecia areata not responding to topicals. Pediatric use starts at 12. Discuss medical history with doctors—contraindicated in active infections or certain cancers.

Conclusion

Litfulo provides an oral option for alopecia areata management in the US. Follow prescribed use and regular check-ups for potential regrowth.